An asymmetric synthesis of novel aminocyclopropyl carboxylic acids (ACC)
Abstract
Cyclopropanation of chiral bicyclic lactams 2 followed by removal of the chiral auxiliary and a Curtius rearrangement leads to the title compounds in >99% e.e.
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J. Chem. Soc., Chem. Commun., 1995, 141-142
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An asymmetric synthesis of novel aminocyclopropyl carboxylic acids (ACC)
M. Es-Sayed, P. Devine, L. E. Burgess, A. de Meijere and A. I. Meyers, J. Chem. Soc., Chem. Commun., 1995, 141 DOI: 10.1039/C39950000141
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