SCHEDULED MAINTENANCE
2,4-Diaza-4-deoxypodophyllotoxin 4 and its cis analogue 14 are synthesised stereoselectively from 3,4-methylenedioxyaniline 5, and show significant activity against vincristine-resistant P-388 leukaemia in vivo.
Y. Hitotsuyanagi, Y. Naka, K. Yamagami, A. Fujii and T. Tahara, J. Chem. Soc., Chem. Commun., 1995, 49 DOI: 10.1039/C39950000049
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