Issue 1, 1995

A cyclization reaction catalysed by antibodies

Abstract

Monoclonal antibodies, elicited by transition-state analogues for either exo- or endo-lactonization of α-trifluoromethyl-γ,δ-unsaturated acids, catalyse the regiospecific formation of corresponding γ- or δ-lactones; the exo-lactonization proceeds with high diastereospecificity.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1995, 39-40

A cyclization reaction catalysed by antibodies

T. Kitazume and M. Takeda, J. Chem. Soc., Chem. Commun., 1995, 39 DOI: 10.1039/C39950000039

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