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Issue 14, 1994
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Design and synthesis of transition-state analogues for a cationic cyclisation

Abstract

Transition-state analogues based upon the 6-(hydroxymethyl)-13-azagona-1,3,5(10),8-tetraene structure (e.g., 40) have been designed and synthesized as part of a programme to elicit antibodies capable of catalysing cationic cyclisations. Methodology for conjugating such analogues to proteins has also been developed.

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Article type: Paper
DOI: 10.1039/P19940001997
Citation: J. Chem. Soc., Perkin Trans. 1, 1994,0, 1997-2006

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    Design and synthesis of transition-state analogues for a cationic cyclisation

    I. M. Bell, C. Abell and F. J. Leeper, J. Chem. Soc., Perkin Trans. 1, 1994, 0, 1997
    DOI: 10.1039/P19940001997

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