1, 3-Dipolar cycloaddition of nitrite oxides to enamines formed from protected γ-amino- or γ-hydroxy-β-keto esters affords isoxazolecarboxylic esters that can be converted into 3-acyltetramic acids via dihydropyrroloisoxazol-4-ones, or into 3-acyltetronic acids.
R. C. F. Jones, G. Bhalay, P. A. Carter, K. A. M. Duller and S. I. E. Vulto, J. Chem. Soc., Perkin Trans. 1, 1994, 2513 DOI: 10.1039/P19940002513
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