Reaction of silyl enol ethers with arenediazonium salts. Part 2. α-Amination of esters
Abstract
Diazonium salts efficiently serve as electrophilic aminating reagents of esters. The reaction of arenediazonium tetrafluoroborates with ketene silyl ketals yielded α-azo or α-hydrazono esters in good to excellent yields under very mild conditions. Hydrogenation of those esters gave α-amino esters quantitatively.