Issue 21, 1994

Synthesis of the A/E/F tricyclic section of the norditerpenoid alkaloid methyllycaconitine, a potent inhibitor of neurotransmission

Abstract

The tricyclic amine (±)-2; R = H, with five stereogenic centres, representing the A/E/F ring system of the norditerpene alkaloid methyllycaconitine, is synthesised from penta-1,4-dien-3-ol in nine steps, with overall yield 16%.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 2487-2488

Synthesis of the A/E/F tricyclic section of the norditerpenoid alkaloid methyllycaconitine, a potent inhibitor of neurotransmission

L. C. Baillie, J. R. Bearder and D. A. Whiting, J. Chem. Soc., Chem. Commun., 1994, 2487 DOI: 10.1039/C39940002487

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