A radical cyclisation approach to the 2-oxabicyclo[2.2.1]heptane ring system
Abstract
Intramolecular cyclisations of radicals generated from the β-substituted tetrahydrofurans 6, 7 and 14c onto suitably positioned alkene functions attached to the α′-position of the heterocycle give good to excellent yields of the 2-oxabicyclo[2.2.1]heptanes 8, 9 and 16.