The mutagenic lesion 3,N4-etheno-2′-deoxycytidine (εdC) greatly destabilises DNA when paired with each of the natural bases although the solution structure of a duplex containing a εC : A pair shows that the lesion does not greatly disrupt base pairing in the duplex.
N. J. Gibson, J. A. Parkinson, T. Barlow, W. P. Watson and T. Brown, J. Chem. Soc., Chem. Commun., 1994, 2241 DOI: 10.1039/C39940002241
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