Approaches to the assembly of the antifungal agent FR-900848: studies on the asymmetric synthesis of bicyclopropanes and an X-ray crystallographic analysis of (4R,5R)-2-[(1R,3S,4S,6R)-6-phenyl-1-bicyclopropyl]-1,3-dimethyl-4,5-diphenylimidazolidine

Anthony G. M. Barrett; Wendel W. Doubleday; Gary J. Tustin; Andrew J. P. White; David J. Williams

doi:10.1039/C39940001783

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Approaches to the assembly of the antifungal agent FR-900848: studies on the asymmetric synthesis of bicyclopropanes and an X-ray crystallographic analysis of (4R,5R)-2-[(1R,3S,4S,6R)-6-phenyl-1-bicyclopropyl]-1,3-dimethyl-4,5-diphenylimidazolidine

Anthony G. M. Barrett, Wendel W. Doubleday, Gary J. Tustin, Andrew J. P. White and David J. Williams

Abstract

Both syn- and anti-bicyclopropane derivatives are efficiently prepared with good relative and absolute stereocontrol; structures are unequivocally determined by an X-ray crystallographic study of the title imidazolidine derivative.

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DOI: https://doi.org/10.1039/C39940001783
Article type: Paper

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J. Chem. Soc., Chem. Commun., 1994, 1783-1784

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Approaches to the assembly of the antifungal agent FR-900848: studies on the asymmetric synthesis of bicyclopropanes and an X-ray crystallographic analysis of (4R,5R)-2-[(1R,3S,4S,6R)-6-phenyl-1-bicyclopropyl]-1,3-dimethyl-4,5-diphenylimidazolidine

A. G. M. Barrett, W. W. Doubleday, G. J. Tustin, A. J. P. White and D. J. Williams, J. Chem. Soc., Chem. Commun., 1994, 1783 DOI: 10.1039/C39940001783

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Journal of the Chemical Society, Chemical Communications

Approaches to the assembly of the antifungal agent FR-900848: studies on the asymmetric synthesis of bicyclopropanes and an X-ray crystallographic analysis of (4R,5R)-2-[(1R,3S,4S,6R)-6-phenyl-1-bicyclopropyl]-1,3-dimethyl-4,5-diphenylimidazolidine

Abstract

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Download Citation

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Approaches to the assembly of the antifungal agent FR-900848: studies on the asymmetric synthesis of bicyclopropanes and an X-ray crystallographic analysis of (4R,5R)-2-[(1R,3S,4S,6R)-6-phenyl-1-bicyclopropyl]-1,3-dimethyl-4,5-diphenylimidazolidine

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