SCHEDULED MAINTENANCE
A strategy for a total synthesis of the cytotoxic dimeric macrolide swinholide A (1, Scheme 1) is outlined and a stereoselective construction of the suitably functionalized C3–C17 fragment 4, starting with building blocks 6, 7, 9 and 10 is described.
A. P. Patron, P. K. Richter, M. J. Tomaszewski, R. A. Miller and K. C. Nicolaou, J. Chem. Soc., Chem. Commun., 1994, 1147 DOI: 10.1039/C39940001147
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