A new N-acetylneuraminic acid donor for highly stereoselective α-sialylation
Abstract
The new sialyl donor 6(prepared from N-acetylneuraminic acid in 44% yield over six steps) effects clean α-sialylation of 2-(trimethylsilyl)ethyl 2,3,6,2′,4′,6′-hexabenzyl-β-D-lactoside in 67% yield.