Issue 6, 1994

The mechanism of Escherichia coli dethiobiotin synthetase—the closure of the ureido ring of dethiobiotin involves formation of a carbamic-phosphate mixed anhydride

Abstract

The final intermediate in the enzymatic synthesis of the ureido ring of D-dethiobiotin 1 from (7R,8S)-7,8-diaminononanoate 2 catalysed by E. coli dethiobiotin synthetase is the phosphoric acid anydride 4 of the carbamate 3.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 759-760

The mechanism of Escherichia coli dethiobiotin synthetase—the closure of the ureido ring of dethiobiotin involves formation of a carbamic-phosphate mixed anhydride

R. L. Baxter and H. C. Baxter, J. Chem. Soc., Chem. Commun., 1994, 759 DOI: 10.1039/C39940000759

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