Issue 4, 1994

Total synthesis of dephostatin, a novel protein tyrosine phosphatase inhibitor

Abstract

The first synthesis of dephostatin, conducted by use of a silyl protective group removable with HF–NaF buffer without damaging the labile N-nitrosamino group, is described.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 437-438

Total synthesis of dephostatin, a novel protein tyrosine phosphatase inhibitor

T. Watanabe, T. Takeuchi, M. Otsuka and K. Umezawa, J. Chem. Soc., Chem. Commun., 1994, 437 DOI: 10.1039/C39940000437

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