1-Hydroxy-7-azabenzotriazole (HOAt) and its corresponding uronium and phosphonium salts are shown to be superior to their benzotriazole analogs in solid-phase peptide synthesis, thereby making possible the automated synthesis of peptides containing hindered amino acids.
L. A. Carpino, A. El-Faham, C. A. Minor and F. Albericio, J. Chem. Soc., Chem. Commun., 1994, 201 DOI: 10.1039/C39940000201
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