The binding of alkyl chains to β-cyclodextrin and ‘hydroxypropyl-β-cyclodextrin’
Abstract
The strength of binding of aliphatic alcohols, alkanesulfonate ions and aryl alkanoates to ‘hydroxypropyl-β-cyclodextrin’ is very similar to that to unmodified β-cyclodextrin (β-CD). The clear inference is that both forms of β-CD bind these guests to the wider opening of the CD cavity that is surrounded by secondary hydroxy groups.