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Issue 18, 1993
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Formation of a new toxic compound, citrinin H1, from citrinin on mild heating in water

Abstract

Citrinin, a relatively weak mycotoxin, can be detoxified by heating; however, a compound having high toxicity was formed on heating at 140 °C in the presence of water. The toxic compound was isolated from heated citrinin and its structure was determined. Its toxicity, evaluated by cytotoxicity assay, was 10-fold higher on a weight basis than that of citrinin. This new compound was named citrinin H1, which was also formed by heating citrinin at 100 °C for 30 min.

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Article information


J. Chem. Soc., Perkin Trans. 1, 1993, 2167-2171
Article type
Paper

Formation of a new toxic compound, citrinin H1, from citrinin on mild heating in water

A. B. Trivedi, M. Hirota, E. Doi and N. Kitabatake, J. Chem. Soc., Perkin Trans. 1, 1993, 2167
DOI: 10.1039/P19930002167

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