Issue 10, 1993

Total synthesis of (+)-kifunensine, a potent glycosidase inhibitor

Abstract

(+)-Kifunensine, a potent inhibitor of mannosidase I, has been synthesized in 13 steps from chlorobenzene by microbial oxygenation with Pseudomonas putida 39D and stereocontrolled peripheral functionalization of cis-3-chlorocyclohexa-3,5-dienediol 3.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1993, 1095-1097

Total synthesis of (+)-kifunensine, a potent glycosidase inhibitor

J. Rouden and T. Hudlicky, J. Chem. Soc., Perkin Trans. 1, 1993, 1095 DOI: 10.1039/P19930001095

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