Examples are given illustrating the use of ortho-substituents on substituted benzene rings as steric buttresses to limit the conformational space available to a dipole and dipolarophile, forcing them into closer proximity and hence to allow cycloadditions to proceed that otherwise do not.
B. S. Orlek, P. G. Sammes and D. J. Weller, J. Chem. Soc., Chem. Commun., 1993, 1412 DOI: 10.1039/C39930001412
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