Issue 15, 1993

Solution structure of the antitumour antibiotic neocarzinostatin, a chromophore–protein complex

Abstract

The chromophore-binding structure of the neocarzinostatin complex is determined for the first time by two-dimensional 1H NMR spectroscopy, and reveals the elements of the specific binding and the stabilization interactions of the unstable dienediyne chromophore by the apoprotein.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1993, 1205-1207

Solution structure of the antitumour antibiotic neocarzinostatin, a chromophore–protein complex

T. Tanaka, M. Hirama, K. Fujita, S. Imajo and M. Ishiguro, J. Chem. Soc., Chem. Commun., 1993, 1205 DOI: 10.1039/C39930001205

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