Formal syntheses of hepoxilin B3, trioxilin B3 and substances against rice blast disease from D-mannitol
Abstract
A pair of epimeric key intermediates for preparation of the title compounds are readily available from 1,2 : 3,4 : 5,6-tri-O-isopropylidene-D-mannitol via selective cleavage of acetonide and lactol-formation-induced epimerization.