Optically active cis- and trans-1-chloro-2-methoxycarbonyl-2-methylcarbamoylaziridines. Stereochemical properties
Abstract
The synthesis of optically active cis- and trans-1-chloro-2-methoxycarbonyl-2-methylcarbamoylaziridines (2) is described and their relative stability determined by thermal equilibration. The crystal structure of (±)-cis-2 was determined by X-ray diffraction analysis and compared with that of (–)-trans-2. The chiroptical properties and configurational correlations with the parent compound (+)-1-chloro-2,2-bismethoxycarbonylaziridine (1) are reported.