The carboxy group of amphotericin B 1 has been converted into a range of ketone analogues 12–15via a strategy based on the use of protecting groups to facilitate derivatisation of 1.
M. J. Driver, A. R. Greenlees and D. T. MacPherson, J. Chem. Soc., Perkin Trans. 1, 1992, 3155 DOI: 10.1039/P19920003155
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