We describe a number of synthetic approaches to 4-cyanoprogresterone. This compound is a potent inhibitor, both in vitro and in vivo of the enzyme 5-alpha-reductase
M. Haase-Held, M. Hatzis and J. Mann, J. Chem. Soc., Perkin Trans. 1, 1992, 2999 DOI: 10.1039/P19920002999
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