The phosphonates 19, 20, 24, 27 and the diphosphorylphosphonates 10 and 11 have been prepared as mimics of nucleoside-phosphates and -triphosphates respectively. The compounds 10 and 11 were found to be potent inhibitors of human immunodeficiency virus reverse transcriptase (HIV-rt).
D. M. Coe, S. M. Roberts and R. Storer, J. Chem. Soc., Perkin Trans. 1, 1992, 2695 DOI: 10.1039/P19920002695
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