A new practical procedure for the enzymatic resolution of 1,2-diols 1a–e has been developed by lipase-catalysed regio- and enantio-selective esterification using anhydrides as acylating agents in organic solvents.
A. Bosetti, D. Bianchi, P. Cesti, P. Golini and S. Spezia, J. Chem. Soc., Perkin Trans. 1, 1992, 2395 DOI: 10.1039/P19920002395
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