Simple synthesis of furanoid and dioxabicyclo[3.3.0]octane lignans
Abstract
The key intermediates, the keto lactones 5, 6 obtained by convergent synthesis, were transformed into furanoid and dioxabicyclo[3.3.0]octane lignan analogues 7, 8 by means of sodium borohydride reduction and subsequent acid-catalysed cyclisation.