[2 + 2]Cycloaddition of the 1,1-dimethoxyalkenes 1 to acetylenic esters, such as dimethyl acetylenedicarboxylate 2a and methyl propiolate 2b, occurs via 1,4-dipolar intermediates which, trapped by methyl propiolate and tert-butyl alcohol, give functionalized 3,3-dimethoxycyclobutenes 3, synthetic precursors to naturally occurring products and biologically active compounds.
M. L. Graziano, M. R. Lesce, F. Cermola and G. Cimminiello, J. Chem. Soc., Perkin Trans. 1, 1992, 1269 DOI: 10.1039/P19920001269
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