Issue 2, 1992

Biosynthesis of vitamin B12: use of a single 13C label in the macrocycle to confirm C-11 methylation in precorrin-6x

Abstract

[11-13C]Uro'gen III is unambiguously synthesised for enzymic conversion into precorrin-6x which as its octamethyl ester gives a 13C NMR spectrum confirming the presence of a C-11 methyl group.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1992, 138-139

Biosynthesis of vitamin B12: use of a single 13C label in the macrocycle to confirm C-11 methylation in precorrin-6x

F. Blanche, M. Kodera, M. Couder, F. J. Leeper, D. Thibaut and A. R. Battersby, J. Chem. Soc., Chem. Commun., 1992, 138 DOI: 10.1039/C39920000138

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