Tritium labelled ibogaine, for pharmacological studies as an anti-addiction treatment for cocaine abuse, is prepared by a new method for the tritiation of aryl compounds involving ortho metallation followed by facile reduction of the carbon–metal bond.
H. H. Seltman, D. F. Odear, F. I. Carroll and C. D. Wyrick, J. Chem. Soc., Chem. Commun., 1992, 1757 DOI: 10.1039/C39920001757
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