Issue 22, 1992
From the journal:

Journal of the Chemical Society, Chemical Communications

NMR studies of the Na+, Mg2+ and Ca2+ complexes of cyclosporin A

John A. Carver,   Nicholas H. Rees,   David L. Turner,   Simon J. Senior  and  Babur Z. Chowdhry  

Abstract

The immunosuppressant cyclosporin A has been shown by NMR spectroscopy to form complexes with Na+, Ca2+ and Mg2+ in acetonitrile; Ca2+ and Mg2+ form 1 : 1 complexes and the conformation of cyclosporin A changes dramatically upon binding of the metal ions.

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C39920001682
Article type
Paper

J. Chem. Soc., Chem. Commun., 1992, 1682-1684

Permissions

Request permissions

NMR studies of the Na+, Mg2+ and Ca2+ complexes of cyclosporin A

J. A. Carver, N. H. Rees, D. L. Turner, S. J. Senior and B. Z. Chowdhry, J. Chem. Soc., Chem. Commun., 1992, 1682 DOI: 10.1039/C39920001682

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements