New tris(hydroxymethyl)amidomethane and other non-ionic polyols derived from Cannizzaro condensations are reported, which feature molecular masses and carbon atom to hydroxy group ratios similar to those of sucrose; these materials are (in vitro) non-fermentable and accurately reproduce the non-gustatory properties of sucrose, which renders them useful as sugar macronutrient substitutes in low-calorie formulated foods.
G. E. DuBois, B. Zhi, G. M. Roy, S. Y. Stevens and M. Yalpani, J. Chem. Soc., Chem. Commun., 1992, 1604 DOI: 10.1039/C39920001604
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