Issue 21, 1992

Synthesis and biological actions of optically active enediynes related to dynemicin A

Abstract

Enantiomerically pure enediynes (+)-2 and (–)-2 were synthesized using a chiral resolution method and were shown to exhibit different cytotoxicities against a number of tumour cells.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1992, 1542-1544

Synthesis and biological actions of optically active enediynes related to dynemicin A

K. C. Nicolaou, Y. P. Hong, W.-M. Dai, Z.-J. Zeng and W. Wrasidlo, J. Chem. Soc., Chem. Commun., 1992, 1542 DOI: 10.1039/C39920001542

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