1-Thia-3,8-diyn-5-ene compounds 5–10, which are derivatives of the parent compound 1 are synthesized in a short step with high stability; these compounds show DNA-cleaving activity under basic conditions in the absence of any additives.
K. Toshima, K. Ohta, A. Ohashi, A. Ohtsuka, M. Nakata and K. Tatsuta, J. Chem. Soc., Chem. Commun., 1992, 1306 DOI: 10.1039/C39920001306
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