Issue 14, 1992

An enzyme-scissile linker for solid-phase peptide synthesis

Abstract

We describe a new linker that contains a phosphodiester moiety for solid-phase peptide synthesis; after completion of the cycle of coupling and deprotection steps, the phosphodiester can be cleaved with phosphodiesterase.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1992, 1033-1034

An enzyme-scissile linker for solid-phase peptide synthesis

D. T. Elmore, D. J. S. Guthrie, A. D. Wallace and S. R. E. Bates, J. Chem. Soc., Chem. Commun., 1992, 1033 DOI: 10.1039/C39920001033

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