Issue 10, 1992

Probing protein conformation by a combination of electrospray mass spectrometry and molecular modelling

Abstract

Electrospray-ionisation mass spectrometry and molecular modelling have been used to probe two conformations of tuna cytochrome c; the number of protons which could be exchanged by deuterons was in remarkable agreement with that calculated using an algorithm for the determination of solvent-accessible surface.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1992, 761-764

Probing protein conformation by a combination of electrospray mass spectrometry and molecular modelling

C. Brown, P. Camilleri, N. J. Haskins and M. Saunders, J. Chem. Soc., Chem. Commun., 1992, 761 DOI: 10.1039/C39920000761

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