A novel 5-enolpyruvylshikimate-3-phosphate synthase (EPSP) inhibitor has been prepared by employing a sulfoxide moiety to mimic the carbocationic centre of the phosphoenolpyruvate (PEP) carbonium ion intermediate.
M. K. Mao, J. E. Franz and J. E. Ream, J. Chem. Soc., Chem. Commun., 1992, 556 DOI: 10.1039/C39920000556
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