A synthesis of aryl C-glycosides via polyketides
Abstract
3,5,9,11-Tetraoxotridecanedioates containing C-glycoside units on the side chain were generated from 1-hydroxy sugars, β-ketoglutarate and acetoacetate; intramolecular condensation of the polyketide compounds gave C-glycosidic naphthalene-1,8-diols regio- and stereo-selectively.