A fast, general, low-temperature rearrangement of ortho-iodobenzyl esters, triggered by lithium–iodine exchange, leads to isobenzofurans which are intercepted in situ by inter and intramolecular Diels–Alder (IMDA) reactions to produce a variety of carbocycles including natural lignans and steroids.
S. Horne and R. Rodrigo, J. Chem. Soc., Chem. Commun., 1992, 164 DOI: 10.1039/C39920000164
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