Synthesis of tin(IV) vanadopyrophosphate as a novel stationary phase for high-performance liquid chromatography and its application to amino acid analysis

Abstract

The preparation and ion-exchange properties of a novel microcrystalline ion exchanger, tin(IV) vanadopyrophosphate (SVPP), were studied. The exchanger has a high ion-exchange capacity (3.17 mequiv g^–1), and its chemical and thermal stabilities are excellent. It was used as a stationary phase for the high-performance ion-exchange chromatographic separation of amino acids. Optimum conditions for high-performance liquid chromatography were investigated. Five amino acids were separated rapidly on a short SVPP column.