3-Hydroxypyrroles and 1H-pyrrol-3(2H)-ones. Part 11. 1H and 13C NMR spectra of 1-substituted and 1,2-disubstituted 3-hydroxy- and 3-alkoxy-pyrroles

Abstract

The ¹H and ¹³C NMR parameters of a range of 1-substituted and 1,2-disubstituted 3-hydroxy- and 3-alkoxy-pyrroles are reported. Typical values for 1-tert-butyl-3-hydroxypyrrole (J values in Hz) are: δ_H 5.50 (³J_4,5 2.9, ⁴J_2,4 2.0, 4-H), 6.26 (⁴J_2,4 2.0 and ⁴J_2,5 2.6, 2-H) and 6.49 (³J_4,5 2.9 and ⁴J_2,5 2.6, 5-H); δ_C 97.60 (¹J_{4 – H} 167.9, ²J_{5 – H} and ³J_{2 – H} 6.8, C-4), 101.16 (¹J_{2 – H} 182.7,³J_{4 – H} and ³J_{5 – H} 4.3, C-2), 114.18 (¹J_{5 – H} 182.5, ²J_{4 – H} and ³J_{2 – H} 6.9, C-5) and 143.37 (²J_{2 – H} 4.3, ³J_{5 – H} 9.0, C-3).