The triphosphate 11 has been synthesised in eight steps from 6-oxabicyclo[3.1.0]hex-2-ene 6 and has been shown to inhibit the enzyme, human immunodeficiency virus reverse transcriptase (HIV-rt).
D. M. Coe, D. C. Orr, S. M. Roberts and R. Storer, J. Chem. Soc., Perkin Trans. 1, 1991, 3378 DOI: 10.1039/P19910003378
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