N-Alkylation of the β-lactone derived from Boc-L-serine followed by ring opening with sodium benzeneselenoate provides chiral substrates which undergo intramolecular radical cyclization to afford cis/trans mixtures of 4-alkyl-L-prolines.
F. Soucy, D. Wernic and P. Beaulieu, J. Chem. Soc., Perkin Trans. 1, 1991, 2885 DOI: 10.1039/P19910002885
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