The (1R, 4S)-acetate 3 and the (1S, 4S)-alcohol 5 have been obtained optically pure by lipase catalysed esterification: compounds 3 and 5 have been converted into carbocyclic dideoxydidehydronucleosides and aristeromycin 9.
S. M. Roberts and K. A. Shoberu, J. Chem. Soc., Perkin Trans. 1, 1991, 2605 DOI: 10.1039/P19910002605
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