Carbonyl allylation by vinyl epoxides with SnCl2–TBA or SnCl2–Lil: application to the diastereoselective synthesis of 1,3-diols
Abstract
Vinyl epoxides reacted with aldehydes in the presence of stannous chloride-tetrabutylammonium bromide or stannous chloride–lithium iodide to produce 2-vinyl-1,3-diols regio- and diastereoselectively.