Secondary mould metabolites. Part 31. Isolation and structure elucidation of illudins A and B, and illudalenol, new sesquiterpenoids from Clitocybe illudens

Abstract

The structure and relative configuration of the three novel sesquiterpenes illudin A 4, illudin B 5 and illudalenol 6, which were isolated from cultures of Clitocybe illudens(=Omphalotus olearius), have been determined on the basis of ¹H NMR, ¹³C NMR and 2D NMR (¹H–¹³C HETCOR and ¹H–¹³C COLOC) studies to be (2S*,4S*)-2,4-dihydroxyillud-5(9)-en-1-one, (2R*,4S*,6S*,8R*)-2,4,6,8 tetrahydroxyillud-5(9)-en-1-one and 4,2-dihydroxyilludala-2,5(9)-dien-1-one, respectively.