Isolation and structure of a new 1-decalone derivative, rapiculine, from Ramichloridium apiculatum

Abstract

A new compound, designated rapiculine 1, was isolated along with fumigatin oxide 2 and spinulosin 3 from the culture filtrate of Ramichloridium apiculatum incubated in Czapek–Dox medium supplemented with 0.2% yeast extract, whereas only fumigatin oxide 2 was isolated from the culture filtrate of the same fungus cultivated in potato-dextrose medium. The structure of rapiculine 1 was elucidated by both spectroscopic means and its chemical reactions.