The reaction of estradiol and estrone with benzeneselenenyl chloride affords mainly 2-phenylselenenyl adducts which are readily converted into the corresponding 2-halogenated estrogens upon treatment with a variety of reagents.
H. Ali and J. E. van Lier, J. Chem. Soc., Perkin Trans. 1, 1991, 269 DOI: 10.1039/P19910000269
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