Homoleptic vanadium(III) diacetone glucosides: how to make a Lewis acid chiral. Crystal structure of tris-(1,2:5,6-di-O-isopropylidene-α-D-glucofuranosato-κO3)-bis(pyridine)vanadium(III)

Abstract

The synthesis of the first homoleptic glucose derivative of a transition metal was achieved via the protonolysis of [V(C₆H₂Me₃-2,4,6)₃(thf)](thf = tetrahydrofuran) using the monoprotic ligand 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (HL). The complex [VL₃] was converted by addition of pyridine (py) into [VL₃(py)₂] containing a metal chiral centre as shown by X-ray analysis.