The methoxydefluorination of 4,8-dimethyl-6-(p-fluorophenyl)azulene proceeds at 1100 times that of fluorobenzene under the same conditions, and reflects the strongly electron withdrawing nature of the seven-membered ring in the azulene system, in contrast with benzenoid and alkyl substituents in SNAr processes.
R. Bolton and A. J. Pilgrim, J. Chem. Soc., Chem. Commun., 1991, 1745 DOI: 10.1039/C39910001745
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...